Integrators that acclimate plastid RNA homeostasis in response to environmental and metabolic stimuli
This project aims to quantitatively study signalling networks and metabolites that act on selected nucleus encoded RNA-binding proteins (RBPs) involved in stabilisation, processing and translation of chloroplast RNAs. These RBPs function in a gene specific and global manner and thereby enable acclimation of plastid gene expression and photosynthetic performance according to the require-ments of the plant cell. Using an avant-garde set of assays and techniques, the molecular base of responsiveness of plastid transcripts and translation to acclimate chloroplast functions will be investigated and quantitatively assessed (e.g. Manavski et al. 2015, Plant Cell, 27, 2600-2615).